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SystImmune and Bristol Myers Squibb Announce Phase I Results of Iza-bren (EGFR x HER3 ADC) in Advanced Solid TumorsClinical Trial Updates

20 Oct 2025

SystImmune and Bristol Myers Squibb Announce Phase I Results of Iza-bren (EGFR x HER3 ADC) in Advanced Solid Tumors

SystImmune and Bristol Myers Squibb announced the first global Phase I results of iza-bren (BL-B01D1), an EGFR x HER3 bispecific antibody-drug conjuga...

AB Science Announces Initial Phase 1 Data for AB8939 and Venetoclax Combination in Refractory or Relapsed Acute Myeloid LeukemiaClinical Trial Updates

17 Oct 2025

AB Science Announces Initial Phase 1 Data for AB8939 and Venetoclax Combination in Refractory or Relapsed Acute Myeloid Leukemia

AB Science SA announced initial Phase 1 data for the combination of AB8939 with venetoclax for treating refractory or relapsed acute myeloid leukemia ...

Nuvectis Pharma Announces Upcoming Presentations for NXP900 at AACR-NCI-EORTC ConferenceClinical Trial Updates

17 Oct 2025

Nuvectis Pharma Announces Upcoming Presentations for NXP900 at AACR-NCI-EORTC Conference

Nuvectis Pharma, Inc. announced upcoming poster presentations for NXP900 at the 2025 AACR-NCI-EORTC International Conference on Molecular Targets and ...

Praxis Announces Positive Phase 3 Results for Ulixacaltamide in Essential TremorClinical Trial Updates

17 Oct 2025

Praxis Announces Positive Phase 3 Results for Ulixacaltamide in Essential Tremor

Praxis Precision Medicines announced positive topline results from two pivotal Phase 3 studies (Essential3 program) of ulixacaltamide HCl in patients ...

Vor Bio Announces Positive Phase 3 Results of Telitacicept in Systemic Lupus Erythematosus Published in NEJMClinical Trial Updates

17 Oct 2025

Vor Bio Announces Positive Phase 3 Results of Telitacicept in Systemic Lupus Erythematosus Published in NEJM

Vor Bio announces the publication of positive results from a Phase 3 trial in China evaluating telitacicept for systemic lupus erythematosus (SLE) in ...

Aicuris' Pritelivir Meets Primary Endpoint in Phase 3 Trial for Refractory Herpes Simplex Virus in Immunocompromised PatientsClinical Trial Updates

16 Oct 2025

Aicuris' Pritelivir Meets Primary Endpoint in Phase 3 Trial for Refractory Herpes Simplex Virus in Immunocompromised Patients

Aicuris Anti-infective Cures AG announced positive results from its Phase 3 trial (PRIOH-1) of pritelivir for treating refractory Herpes Simplex Virus...

Boehringer and Click Therapeutics present positive Phase III data for CT-155 in SchizophreniaClinical Trial Updates

14 Oct 2025

Boehringer and Click Therapeutics present positive Phase III data for CT-155 in Schizophrenia

Boehringer Ingelheim and Click Therapeutics announced positive results from the Phase III CONVOKE study of CT-155, an investigational prescription dig...

Gilead and Kite Present New Cancer Data at ESMO 2025, Highlighting Trodelvy's Potential in Metastatic TNBCClinical Trial Updates

14 Oct 2025

Gilead and Kite Present New Cancer Data at ESMO 2025, Highlighting Trodelvy's Potential in Metastatic TNBC

Gilead and Kite will present new data at the ESMO 2025 Congress, showcasing progress in cancer treatment. Key highlights include Phase 3 ASCENT-03 stu...

Spago Nanomedical Announces Positive Data and Dose Increase Recommendation for 177Lu-SN201 in Phase I/IIa Tumorad-01 StudyClinical Trial Updates

14 Oct 2025

Spago Nanomedical Announces Positive Data and Dose Increase Recommendation for 177Lu-SN201 in Phase I/IIa Tumorad-01 Study

Spago Nanomedical announced that the Data Monitoring Committee (DMC) recommended a dose increase in the ongoing Phase I/IIa clinical trial Tumorad-01 ...

Encoded Therapeutics Announces Positive Preclinical Data for Non-Opioid Gene Therapy Candidate for Chronic PainClinical Trial Updates

10 Oct 2025

Encoded Therapeutics Announces Positive Preclinical Data for Non-Opioid Gene Therapy Candidate for Chronic Pain

Encoded Therapeutics announced preclinical data for its AAV9 microRNA (miRNA) gene therapy candidate targeting SCN9A (NaV1.7) for chronic pain. The da...

Taysha Gene Therapies Presents New Data on TSHA-102 for Rett Syndrome at CNS Annual MeetingClinical Trial Updates

10 Oct 2025

Taysha Gene Therapies Presents New Data on TSHA-102 for Rett Syndrome at CNS Annual Meeting

Taysha Gene Therapies announced new supplemental data analysis from Part A of the REVEAL Phase 1/2 trials evaluating TSHA-102 in females with Rett syn...

GlyTR Therapeutics Announces Publication of Pan-Cancer Immunotherapy Platform Study in CellClinical Trial Updates

09 Oct 2025

GlyTR Therapeutics Announces Publication of Pan-Cancer Immunotherapy Platform Study in Cell

GlyTR Therapeutics announced the publication of a study in Cell detailing their Glycan-Dependent T cell Recruiter (GlyTR1 & GlyTR2) therapeutics. Thes...

BrYet US Receives Approval to Initiate Phase 1/2 Trial of ML-016 in Advanced Cancers with Lung and/or Liver Involvement in AustraliaClinical Trial Updates

07 Oct 2025

BrYet US Receives Approval to Initiate Phase 1/2 Trial of ML-016 in Advanced Cancers with Lung and/or Liver Involvement in Australia

BrYet US, Inc. has received approval to initiate a first-in-human Phase 1/2 clinical trial of ML-016 in Australia. The trial will evaluate the safety,...

Editas Medicine Announces EDIT-401 Oral Presentation at ESGCT Congress and Participation in Investor ConferencesClinical Trial Updates

07 Oct 2025

Editas Medicine Announces EDIT-401 Oral Presentation at ESGCT Congress and Participation in Investor Conferences

Editas Medicine announced an oral presentation on EDIT-401, a CRISPR gene editing medicine for lowering LDL-cholesterol by upregulating LDLR, at the E...

Myrtelle Announces Encouraging Interim Results from Phase 1/2 Gene Therapy Trial for Canavan DiseaseClinical Trial Updates

07 Oct 2025

Myrtelle Announces Encouraging Interim Results from Phase 1/2 Gene Therapy Trial for Canavan Disease

Myrtelle Inc. announced encouraging interim results from its Phase 1/2 clinical trial of rAAV-Olig001-ASPA (MYR-101), an investigational gene therapy ...

Prilenia and Ferrer Announce Phase 3 ALS Study of Pridopidine at NEALS 2025Clinical Trial Updates

07 Oct 2025

Prilenia and Ferrer Announce Phase 3 ALS Study of Pridopidine at NEALS 2025

Prilenia Therapeutics and Ferrer announced the presentation of their planned pivotal Phase 3 study of pridopidine in Amyotrophic Lateral Sclerosis (AL...

Abivax Announces Positive Results from ABTECT Induction Trials of Obefazimod in Ulcerative Colitis PatientsClinical Trial Updates

06 Oct 2025

Abivax Announces Positive Results from ABTECT Induction Trials of Obefazimod in Ulcerative Colitis Patients

Abivax announced late-breaking presentation of 8-Week ABTECT Induction Trial results in participants with and without prior inadequate response to adv...

Candel Therapeutics to Present CAN-2409 Data at SITC 2025Clinical Trial Updates

06 Oct 2025

Candel Therapeutics to Present CAN-2409 Data at SITC 2025

Candel Therapeutics will present data from its enLIGHTEN™ Discovery Platform and CAN-2409 program in non-small cell lung cancer (NSCLC) at the SITC 20...

DATROWAY® Improves Overall and Progression-Free Survival in Metastatic Triple-Negative Breast CancerClinical Trial Updates

06 Oct 2025

DATROWAY® Improves Overall and Progression-Free Survival in Metastatic Triple-Negative Breast Cancer

AstraZeneca and Daiichi Sankyo's DATROWAY® (datopotamab deruxtecan-dlnk) demonstrated statistically significant and clinically meaningful improvements...

Invivyd Announces U.S. IND Clearance and FDA Alignment for VYD2311 COVID Prevention ProgramClinical Trial Updates

06 Oct 2025

Invivyd Announces U.S. IND Clearance and FDA Alignment for VYD2311 COVID Prevention Program

Invivyd announced that the FDA has cleared its IND application and provided feedback to advance its REVOLUTION clinical program for VYD2311, a vaccine...

Marker Therapeutics Announces First Patient Treated in Off-the-Shelf Program for AML and MDSClinical Trial Updates

06 Oct 2025

Marker Therapeutics Announces First Patient Treated in Off-the-Shelf Program for AML and MDS

Marker Therapeutics announced the treatment of the first patient in their Phase 1 RAPID study, evaluating MT-401, an off-the-shelf (OTS) multi-antigen...

Bolt Biotherapeutics Updates on BDC-4182 and Extends Cash Runway into 2027Clinical Trial Updates

02 Oct 2025

Bolt Biotherapeutics Updates on BDC-4182 and Extends Cash Runway into 2027

Bolt Biotherapeutics announced an update on its Phase 1 dose escalation study of BDC-4182, an ISAC targeting claudin 18.2 for cancer treatment. Initia...

EG 427 Announces Positive Topline Results for EG110A in Neurogenic Bladder PatientsClinical Trial Updates

02 Oct 2025

EG 427 Announces Positive Topline Results for EG110A in Neurogenic Bladder Patients

EG 427 announced positive initial results from a clinical trial of EG110A, a novel DNA therapy for neurogenic bladder. The study showed an over 88% re...

Lisata Therapeutics Announces Positive Preliminary Results from CENDIFOX Trial in Pancreatic CancerClinical Trial Updates

30 Sept 2025

Lisata Therapeutics Announces Positive Preliminary Results from CENDIFOX Trial in Pancreatic Cancer

Lisata Therapeutics announced encouraging preliminary data from the Phase 1/2a CENDIFOX trial evaluating certepetide in combination with FOLFIRINOX fo...

CeleCor Therapeutics Announces Positive Phase 3 Results for Disaggpro in Heart Attack PatientsClinical Trial Updates

24 Sept 2025

CeleCor Therapeutics Announces Positive Phase 3 Results for Disaggpro in Heart Attack Patients

CeleCor Therapeutics announced positive topline results from its Phase 3 CeleBrate trial evaluating Disaggpro™ (zalunfiban) for heart attack treatment...

OS Therapies to Present at BioFuture 2025 and Discuss OST-HER2 Clinical DevelopmentClinical Trial Updates

19 Sept 2025

OS Therapies to Present at BioFuture 2025 and Discuss OST-HER2 Clinical Development

OS Therapies Inc. announces its participation in the BioFuture 2025 conference, where it will present an overview of the company with a focus on the c...

ONWARD Medical Announces Positive Results for ARC-IM Therapy in Blood Pressure Regulation after Spinal Cord InjuryClinical Trial Updates

18 Sept 2025

ONWARD Medical Announces Positive Results for ARC-IM Therapy in Blood Pressure Regulation after Spinal Cord Injury

ONWARD Medical N.V. announced concurrent publications in Nature and Nature Medicine highlighting the benefits of its investigational ARC-IM System for...

Palvella Therapeutics Announces Publication on Rapamycin for Venous MalformationsClinical Trial Updates

18 Sept 2025

Palvella Therapeutics Announces Publication on Rapamycin for Venous Malformations

Palvella Therapeutics announces a publication in Lymphatic Research and Biology highlighting advances in understanding venous malformation pathogenesi...

Protagonist Announces Clinical Data Presentations for Icotrokinra and PN-881 at EADV 2025 CongressClinical Trial Updates

18 Sept 2025

Protagonist Announces Clinical Data Presentations for Icotrokinra and PN-881 at EADV 2025 Congress

Protagonist Therapeutics announced new clinical data for Icotrokinra in plaque psoriasis from Phase 3 ICONIC-ADVANCE and ICONIC-LEAD studies, being pr...

Skyhawk Therapeutics Announces Positive Interim Phase 1 Results for SKY-0515 in Huntington's DiseaseClinical Trial Updates

18 Sept 2025

Skyhawk Therapeutics Announces Positive Interim Phase 1 Results for SKY-0515 in Huntington's Disease

Skyhawk Therapeutics announced positive interim results from its Phase 1 clinical trial of SKY-0515 for Huntington's disease (HD). The trial showed do...

Alto Neuroscience Validates EEG Biomarker for Schizophrenia, Strengthening Phase 2 Trial of ALTO-101Clinical Trial Updates

09 Sept 2025

Alto Neuroscience Validates EEG Biomarker for Schizophrenia, Strengthening Phase 2 Trial of ALTO-101

Alto Neuroscience announced positive results from an independent, prospective replication study validating theta-band inter-trial coherence (ITC) as a...

Atossa Therapeutics Seeks Accelerated Approval for Low-Dose (Z)-Endoxifen for Breast Cancer Risk ReductionClinical Trial Updates

09 Sept 2025

Atossa Therapeutics Seeks Accelerated Approval for Low-Dose (Z)-Endoxifen for Breast Cancer Risk Reduction

Atossa Therapeutics has requested a Type C meeting with the FDA to discuss a regulatory strategy for accelerating the development of low-dose (Z)-endo...

CASI Pharmaceuticals Announces Dose Escalation in Phase 1 CID-103 ITP StudyClinical Trial Updates

09 Sept 2025

CASI Pharmaceuticals Announces Dose Escalation in Phase 1 CID-103 ITP Study

CASI Pharmaceuticals announced that the Safety Monitoring Committee (SMC) recommended dose escalation of CID-103, an anti-CD38 monoclonal antibody, to...

Positive Phase 1/2 Data for IDE397 and Trodelvy Combination in MTAP-Deletion Urothelial CancerClinical Trial Updates

09 Sept 2025

Positive Phase 1/2 Data for IDE397 and Trodelvy Combination in MTAP-Deletion Urothelial Cancer

IDEAYA Biosciences announced positive data from a Phase 1/2 trial evaluating the combination of IDE397, a MAT2A inhibitor, and Trodelvy (sacituzumab g...

Oncolytics Biotech Highlights Pelareorep Efficacy in Metastatic Colorectal CancerClinical Trial Updates

08 Sept 2025

Oncolytics Biotech Highlights Pelareorep Efficacy in Metastatic Colorectal Cancer

Oncolytics Biotech announced positive clinical and translational data for pelareorep in metastatic colorectal cancer (mCRC). In the REO 022 trial, pe...

Positive Phase 1 Data for IDE849 (SHR-4849) in Small Cell Lung CancerClinical Trial Updates

08 Sept 2025

Positive Phase 1 Data for IDE849 (SHR-4849) in Small Cell Lung Cancer

IDEAYA Biosciences and Hengrui Pharma presented positive Phase 1 data for IDE849 (SHR-4849), a DLL3-targeting TOP1 antibody-drug conjugate (ADC), at t...

RYBREVANT® and LAZCLUZE® Combination Prevents Acquired Resistance in First-Line EGFR-Mutated NSCLCClinical Trial Updates

08 Sept 2025

RYBREVANT® and LAZCLUZE® Combination Prevents Acquired Resistance in First-Line EGFR-Mutated NSCLC

Johnson & Johnson announced new analyses from the Phase 3 MARIPOSA study demonstrating that the combination of RYBREVANT® (amivantamab-vmjw) and LAZCL...

Rapport Therapeutics to Announce Topline Phase 2a Results for RAP-219 in Focal Onset SeizuresClinical Trial Updates

08 Sept 2025

Rapport Therapeutics to Announce Topline Phase 2a Results for RAP-219 in Focal Onset Seizures

Rapport Therapeutics will release topline data from its Phase 2a clinical trial of RAP-219 in patients with drug-resistant focal onset seizures on Sep...

Regeneron's Positive Phase 3 Allergy Trials Advance First-in-Class Antibody BlockersClinical Trial Updates

08 Sept 2025

Regeneron's Positive Phase 3 Allergy Trials Advance First-in-Class Antibody Blockers

Regeneron Pharmaceuticals announced positive results from two Phase 3 trials evaluating its first-in-class allergen-blocking antibodies for cat and bi...

iMDx Enrolls First Patient in GraftAssureDx Clinical TrialClinical Trial Updates

08 Sept 2025

iMDx Enrolls First Patient in GraftAssureDx Clinical Trial

Insight Molecular Diagnostics (iMDx) announced the enrollment of the first patient in its clinical trial for GraftAssureDx, a kitted organ transplant ...

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